Autophagy, Apoptosis and Ferroptosis in Oncology: Cell Death and Cancer

Autophagy, Apoptosis and Ferroptosis in Oncology: Cell Death and Cancer

by Kiavash Hushmandi (Author), Alan Prem Kumar (Author)

This book aims to provide a comprehensive exploration of three critical processes involved in cell death and survival, each playing a unique role in cancer development, progression, and treatment. Autophagy, apoptosis, and ferroptosis are distinct yet interconnected pathways that regulate cellular homeostasis and response to stress. In the context of oncology, these processes are of paramount importance. Cancer cells often manipulate autophagy and apoptosis to their advantage, evading death and promoting survival even in the face of therapeutic interventions. Understanding these mechanisms provides valuable insights into how cancer can be effectively targeted and treated. Furthermore, the emerging role of ferroptosis adds an exciting dimension to the ongoing quest for innovative cancer therapies. This book is structured to offer a detailed examination of each process, beginning with their fundamental biological mechanisms, followed by their implications in cancer biology. The chapters are designed to guide the reader through the intricate interplay between autophagy, apoptosis, and ferroptosis, highlighting recent discoveries, ongoing research, and potential therapeutic applications.

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